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Age-Related Macular Degeneration (AMD)

Department of Age-Related Macular Degeneration (AMD)

Age-related macular degeneration is the most common cause of severe loss of eyesight among people 50 and older. Only the center of vision is affected with this disease. It is important to realize that people rarely go blind from it.

AMD affects the central vision, and with it, the ability to see fine details. In AMD, a part of the retina called the macula is damaged. In advanced stages, people lose their ability to drive, to see faces, and to read smaller print. In its early stages, AMD may have no signs or symptoms, so people may not suspect they have it.

Types

The two primary types of age-related macular degeneration have different causes:

1.Dry: This type is the most common. About 80% of those with AMD have the dry form. Its exact cause is unknown, although both genetic and environmental factors are thought to play a role. This happens as the light-sensitive cells in the macula slowly break down, generally one eye at a time. The loss of vision in this condition is usually slow and gradual. It is believed that the age-related damage of an important support membrane under the retina contributes to dry age-related macular degeneration.

2.Wet: Though this type is less common, it usually leads to more severe vision loss in patients than dry AMD. It is the most common cause of severe loss of vision. Wet AMD happens when abnormal blood vessels start to grow beneath the retina. They leak fluid and blood — hence the name wet AMD — and can create a large blind spot in the center of the visual field.

Diagnosis

1.Dilated Eye Exam: Evaluates the retina and macula for signs of AMD.

2.Amsler Grid Test: Checks for distortion or blurred areas in central vision.

3.Fluorescein Angiography: Uses a dye to highlight blood vessels in the retina.

4.Optical Coherence Tomography (OCT): Provides detailed images of the retina’s layers.

Treatment

1.Dry AMD:

  • Lifestyle Changes: Nutritious diet, regular exercise, and smoking cessation.
  • Nutritional Supplements: Antioxidant vitamins and minerals (AREDS2 formula).
  • Low Vision Aids: Devices to assist with impaired vision.


2.Wet AMD:

  • Anti-VEGF Injections: Medications to inhibit abnormal blood vessel growth.
  • Laser Therapy: Photodynamic therapy to seal leaking blood vessels.
  • Retinal Photocoagulation: Laser treatment to destroy abnormal blood vessels.

Age-Related Macular Degeneration (AMD) Overview

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